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Article

Loss of PRC2 function promotes MPNST pathogenesis.

Cancer discovery - 1 Nov 2014

Abstract excerpt

Genetic inactivation of PRC2 components, NF1, and CDKN2A are frequently detected in MPNSTs.

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Identifiers

PMID: 25367955
DOI: 10.1158/2159-8290.CD-RW2014-206

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Loss of PRC2 function promotes MPNST pathogenesis.PMID 25367955Read ↗

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PRC2 loss drives MPNST metastasis and matrix remodeling.Semantic proximity Read ↗

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Chromosomal translocations inactivating CDKN2A support a single path for malignant peripheral nerve sheath tumor initiation.Semantic proximity Read ↗

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