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Article

Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy.

Molecular therapy : the journal of the American Society of Gene Therapy - 1 Feb 2015

Lam Sharon, Sung Julia, Cruz Conrad, Castillo-Caro Paul, Ngo Minhtran, Garrido Carolina, Kuruc Joann, Archin Nancie, Rooney Cliona, Margolis David, Bollard Catherine

Abstract excerpt

Antiretroviral therapy (ART) is unable to eradicate human immunodeficiency virus type 1 (HIV-1) infection. Therefore, there is an urgent need to develop novel therapies for this disease to augment anti-HIV immunity. T cell therapy is appealing in this regard as T cells have the ability to proliferate, migrate, and their antigen specificity reduces the possibility of off-target effects. However, past human studies...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25366030
DOI: 10.1038/mt.2014.207
PMCID: PMC4445615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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