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The Emerging Role for CTL Epitope Specificity in HIV Cure Efforts

6 Jul 2020

Abstract excerpt

The development of an effective human immunodeficiency virus (HIV) cure is a critical global health priority. A major obstacle to this effort is the establishment of a latent reservoir of HIV infected cells, which necessitates lifelong therapy, causing both logistical and adherence burdens for infected individuals. However, in a subset of these individuals, cytotoxic T lymphocytes (CTLs) can durably suppress...

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PMID: 33586771
DOI: 10.1093/infdis/jiaa333

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