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Article

Single-cell copy number analysis of prostate cancer cells captured with geometrically enhanced differential immunocapture microdevices.

Analytical chemistry - 18 Nov 2014

Pratt Erica D, Stepansky Asya, Hicks James, Kirby Brian J

Abstract excerpt

Limited access to tumor tissue makes repeated sampling and real-time tracking of cancer progression infeasible. Circulating tumor cells (CTCs) provide the capacity for real-time genetic characterization of a disseminating tumor cell population via a simple blood draw. However, there is no straightforward method to analyze broadscale genetic rearrangements in this heterogeneous cell population at the single cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25363873
DOI: 10.1021/ac503453v

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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