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Characterization of a novel automated microfiltration device for the efficient isolation and analysis of circulating tumor cells from clinical blood samples.

Scientific reports - 5 May 2020

Yee-de León Juan F, Soto-García Brenda, Aráiz-Hernández Diana, Delgado-Balderas Jesús Rolando, Esparza Miguel, Aguilar-Avelar Carlos, Wong-Campos J D, Chacón Franco, López-Hernández José Y, González-Treviño A Mauricio, Yee-de León José R, Zamora-Mendoza Jorge L, Alvarez Mario M, Trujillo-de Santiago Grissel, Gómez-Guerra Lauro S, Sánchez-Domínguez Celia N, Velarde-Calvillo Liza P, Abarca-Blanco Alejandro

Abstract excerpt

The detection and analysis of circulating tumor cells (CTCs) may enable a broad range of cancer-related applications, including the identification of acquired drug resistance during treatments. However, the non-scalable fabrication, prolonged sample processing times, and the lack of automation, associated with most of the technologies developed to isolate these rare cells, have impeded their transition into the...

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Cell Separation
Filtration
Neoplasm Metastasis
Neoplastic Cells, Circulating

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pattern Recognition, Automated

Prostatic Neoplasms

Receptors, Androgen

Reproducibility of Results

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Open in PubMed Open full text

Identifiers

PMID: 32372001
DOI: 10.1038/s41598-020-63672-7
PMCID: PMC7200708

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