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Article

Early and exudative age-related macular degeneration is associated with increased plasma levels of soluble TNF receptor II.

Acta ophthalmologica - 1 May 2015

Faber Carsten, Jehs Tina, Juel Helene Baek, Singh Amardeep, Falk Mads Krüger, Sørensen Torben Lykke, Nissen Mogens Holst

Abstract excerpt

PURPOSE: We have recently identified homeostatic alterations in the circulating T cells of patients with age-related macular degeneration (AMD). In cultures of retinal pigment epithelial cells, we have demonstrated that T-cell-derived cytokines induced the upregulation of complement, chemokines and other proteins implicated in AMD pathogenesis. The purpose of this study was to test whether increased plasma levels...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25363549
DOI: 10.1111/aos.12581

Genes

CFH
TNF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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