Article
Inflammation and the pathogenesis of age-related macular degeneration.
Expert opinion on therapeutic targets - 1 Jun 2009
Augustin Albert J, Kirchhof Janna
Abstract excerpt
BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of blindness in the Western world. Many changes occur in various areas of the eye as it ages. These include choroidal thinning, thickening of Bruch's membrane and drusen formation. Each of these is associated with the onset of AMD. METHODS: Recent findings on how those changes contribute to the pathogenesis of AMD with a focus on inflammation...
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