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Article

[Role of rotenone in mitochondrial oxidative damage and the underlying mechanisms].

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 1 Oct 2014

Deng Yong, Lu Jun

Abstract excerpt

Rotenone is one of the typical inhibitors of the complex I on the mitochondrial respiratory chain. Numerous studies showed when applied to live animals or cells, rotenone could lead to mitochondrial dysfunction, ROS augment, and thus oxidative damage to proteins, lipids and nucleic acids. Through...

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Identifiers

PMID: 25355263
DOI: 10.11817/j.issn.1672-7347.2014.10.019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25355263-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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