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Rosmarinic acid ameliorated oxidative stress, neuronal injuries, and mitochondrial dysfunctions mediated by polyglutamine and ɑ-synuclein in Caenorhabditis elegans models

2023-05-04

Abstract excerpt

<title>Abstract</title> <p>Numerous natural antioxidants have been developed into agents for neurodegenerative diseases (NDs) treatment. Rosmarinic acid (RA), an excellent antioxidant, exhibits neuroprotective activity, but its anti-NDs efficacy still reminds puzzled. Here, <italic>Caenorhabditis elegans</italic> models were employed to systematically reveal RA-mediated mechanisms in delaying NDs from diverse fac...

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Literature Corpus work
e455972f-a6f6-518e-81ab-5e810f979c64
DOI
10.21203/rs.3.rs-2868747/v1
Open publication

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Rosmarinic acid ameliorated oxidative stress, neuronal injuries, and mitochondrial dysfunctions mediated by polyglutamine and ɑ-synuclein in Caenorhabditis elegans modelsDOI 10.21203/rs.3.rs-2868747/v1
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