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Article

Reactive oxygen species and mitochondrial diseases.

Seminars in cell & developmental biology - 1 Dec 2001

Kirkinezos I G, Moraes C T

Abstract excerpt

A variety of diseases have been associated with excessive reactive oxygen species (ROS), which are produced mostly in the mitochondria as byproducts of normal cell respiration. The interrelationship between ROS and mitochondria suggests shared pathogenic mechanisms in mitochondrial and ROS-related diseases. Defects in oxidative phosphorylation can increase ROS production, whereas ROS-mediated damage to...

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Identifiers

PMID: 11735379
DOI: 10.1006/scdb.2001.0282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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