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Article

The RAD51 135G>C polymorphism is related to the effect of adjuvant therapy in early breast cancer.

Journal of cancer research and clinical oncology - 1 May 2015

Söderlund Leifler K, Asklid A, Fornander T, Stenmark Askmalm M

Abstract excerpt

PURPOSE: RAD51, a central player in the response to DNA damage, has been suspected to contribute to tumour resistance to therapy. A single-nucleotide polymorphism, RAD51 135G>C, in the untranslated region of the RAD51 gene elevates breast cancer risk among BRCA2 carriers. In this study, it was in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25354554
DOI: 10.1007/s00432-014-1859-0

Genes

RAD51
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25354554-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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The RAD51 135G>C polymorphism is related to the effect of adjuvant therapy in early breast cancer.PMID 25354554Read ↗

RAD51 135G/C polymorphism and breast cancer risk: a meta-analysis from 21 studies.Semantic proximity Read ↗

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies.Semantic proximity Read ↗

RAD51 135G>C polymorphism contributes to breast cancer susceptibility: a meta-analysis involving 26,444 subjects.Semantic proximity Read ↗

Association between the RAD51 135 G>C polymorphism and risk of cancer: a meta-analysis of 19,068 cases and 22,630 controls.Semantic proximity Read ↗

RAD51 135G>C polymorphism and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

RAD51 Gene 135G/C polymorphism and the risk of four types of common cancers: a meta-analysis.Semantic proximity Read ↗

RAD51 G135C polymorphism is associated with breast cancer susceptibility: a meta-analysis involving 22,399 subjects.Semantic proximity Read ↗

Polymorphic Variants in 5'-UTR Regions of the RAD51 Gene are Associated With RAD51 Expression and Triple-Negative Breast Cancer (TNBC): A Case-Control Study.Semantic proximity Read ↗

Genetic 135G/C polymorphism of RAD51 gene and risk of cancer: a meta-analysis of 28,956 cases and 28,372 controls.Semantic proximity Read ↗

A single nucleotide polymorphism in the 5' untranslated region of RAD51 and risk of cancer among BRCA1/2 mutation carriers.Semantic proximity Read ↗

RAD51 genotype and triple-negative breast cancer (TNBC) risk in Polish women.Semantic proximity Read ↗

Analysis of the G/C polymorphism in the 5'-untranslated region of the RAD51 gene in breast cancer.Semantic proximity Read ↗

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