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Article

Analysis of the G/C polymorphism in the 5'-untranslated region of the RAD51 gene in breast cancer.

Acta biochimica Polonica - 1 Jan 2003

Blasiak Janusz, Przybyłowska Karolina, Czechowska Agnieszka, Zadrozny Marek, Pertyński Tomasz, Rykała Jan, Kołacińska Agnieszka, Morawiec Zbigniew, Drzewoski Józef

Abstract excerpt

The breast cancer suppressor proteins BRCA1 and BRCA2 interact with RAD51, a protein essential for maintaining genomic stability by playing a central role in homology-dependent recombinational repair of the DNA double-strand breaks. Therefore, genetic variability in the RAD51 gene may contribute to the appearance and/or progression of breast cancer. A single nucleotide polymorphism in the 5'- untranslated region...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12673366

Genes

RAD51
BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Research trail→

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Analysis of the G/C polymorphism in the 5'-untranslated region of the RAD51 gene in breast cancer.PMID 12673366Read ↗

RAD51 135G/C polymorphism and breast cancer risk: a meta-analysis from 21 studies.Semantic proximity Read ↗

Germline BRCA1 mutations and G/C polymorphism in the 5'-untranslated region of the RAD51 gene in Polish women with breast cancer.Semantic proximity Read ↗

[The G/C polymorphism of RAD51 gene in breast cancer].Semantic proximity Read ↗

A single nucleotide polymorphism in the 5' untranslated region of RAD51 and risk of cancer among BRCA1/2 mutation carriers.Semantic proximity Read ↗

RAD51 135G>C does not modify breast cancer risk in non-BRCA1/2 mutation carriers: evidence from a meta-analysis of 12 studies.Semantic proximity Read ↗

RAD51 135G>C polymorphism and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

RAD51 135G>C polymorphism contributes to breast cancer susceptibility: a meta-analysis involving 26,444 subjects.Semantic proximity Read ↗

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies.Semantic proximity Read ↗

Analysis of RAD51 polymorphism and BRCA1 mutations in Polish women with breast cancer.Semantic proximity Read ↗

Polymorphic Variants in 5'-UTR Regions of the RAD51 Gene are Associated With RAD51 Expression and Triple-Negative Breast Cancer (TNBC): A Case-Control Study.Semantic proximity Read ↗

RAD51 G135C polymorphism is associated with breast cancer susceptibility: a meta-analysis involving 22,399 subjects.Semantic proximity Read ↗

RAD51 135G>C polymorphism and risk of familial breast cancer in a South American population.Semantic proximity Read ↗

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