Article
Correcting systematic inflation in genetic association tests that consider interaction effects: application to a genome-wide association study of posttraumatic stress disorder.
JAMA psychiatry - 1 Dec 2014
Almli Lynn M, Duncan Richard, Feng Hao, Ghosh Debashis, Binder Elisabeth B, Bradley Bekh, Ressler Kerry J, Conneely Karen N, Epstein Michael P
Abstract excerpt
IMPORTANCE: Genetic association studies of psychiatric outcomes often consider interactions with environmental exposures and, in particular, apply tests that jointly consider gene and gene-environment interaction effects for analysis. Using a genome-wide association study (GWAS) of posttraumatic...
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