Article
Association of solute carrier family 30 A8 zinc transporter gene variations with gestational diabetes mellitus risk in a Chinese population.
Frontiers in endocrinology - 1 Jan 2023
Zeng Qiaoli, Tan Bing, Han Fengqiong, Huang Xiujuan, Huang Jinzhi, Wei Yue, Guo Runmin
Abstract excerpt
Background: The solute carrier family 30 A8 zinc transporter (SLC30A8) plays a crucial role in insulin secretion. This study aimed to investigate the impact of SLC30A8 gene polymorphisms on gestational diabetes mellitus (GDM). Methods: The research objective was to select 500 patients with GDM and 502 control subjects. Rs13266634 and rs2466293 were genotyped using the SNPscan™ genotyping assay. Statistical tests,...
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