Article
Genetic influences on translation in yeast.
PLoS genetics - 1 Oct 2014
Albert Frank W, Muzzey Dale, Weissman Jonathan S, Kruglyak Leonid
Abstract excerpt
Heritable differences in gene expression between individuals are an important source of phenotypic variation. The question of how closely the effects of genetic variation on protein levels mirror those on mRNA levels remains open. Here, we addressed this question by using ribosome profiling to examine how genetic differences between two strains of the yeast S. cerevisiae affect translation. Strain differences in...
Topics
- Alleles
- Databases, Genetic
- Gene Expression Regulation, Fungal
- Genome, Fungal
- Humans
- Protein Biosynthesis
- RNA, Messenger
- Ribosomes
- Saccharomyces cerevisiae
- Sequence Alignment