Article
minimac2: faster genotype imputation.
Bioinformatics (Oxford, England) - 1 Mar 2015
Fuchsberger Christian, Abecasis Gonçalo R, Hinds David A
Abstract excerpt
UNLABELLED: Genotype imputation is a key step in the analysis of genome-wide association studies. Upcoming very large reference panels, such as those from The 1000 Genomes Project and the Haplotype Consortium, will improve imputation quality of rare and less common variants, but will also increase the computational burden. Here, we demonstrate how the application of software engineering techniques can help to...
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