Article
Pin1 promoter rs2233678 and rs2233679 polymorphisms in cancer: a meta-analysis.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Zhu Yan-Mei, Liu Jing-Wei, Xu Qian, Yuan Yuan
Abstract excerpt
PIN1 is one member of the parvulin PPIase family. By controlling Pro-directed phosphorylation, PIN1 plays an important role in cell transformation and oncogenesis. There are many polymorphisms in the PIN1 gene, including rs2233678 and rs2233679 affecting the PIN1 promoter. Recently, a number of case-control studies were conducted to investigate the association between PIN1 gene rs2233678 and rs2233679...
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