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Inhibition of Influenza Virus Replication by Targeting Broad Host Cell Pathways

21 Oct 2014

Abstract excerpt

Antivirals that are currently used to treat influenza virus infections target components of the virus which can mutate rapidly. Consequently, there has been an increase in the number of resistant strains to one or many antivirals in recent years. Here we compared the antiviral effects of lysosomotropic alkalinizing agents (LAAs) and calcium modulators (CMs), which interfere with crucial events in the influenza...

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PMID: 25333287
DOI: 10.1371/journal.pone.0110631

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