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Article

CD271 mediates stem cells to early progeny transition in human epidermis.

The Journal of investigative dermatology - 1 Mar 2015

Truzzi Francesca, Saltari Annalisa, Palazzo Elisabetta, Lotti Roberta, Petrachi Tiziana, Dallaglio Katiuscia, Gemelli Claudia, Grisendi Giulia, Dominici Massimo, Pincelli Carlo, Marconi Alessandra

Abstract excerpt

CD271 is the low-affinity neurotrophin (p75NTR) receptor that belongs to the tumor necrosis factor receptor superfamily. Because in human epidermis, CD271 is predominantly expressed in transit-amplifying (TA) cells, we evaluated the role of this receptor in keratinocyte differentiation and in the transition from keratinocyte stem cells (KSCs) to progeny. Calcium induced an upregulation of CD271 in subconfluent...

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Identifiers

PMID: 25330297
DOI: 10.1038/jid.2014.454

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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