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Article

Beneficial effects of environmental enrichment and food entrainment in the R6/2 mouse model of Huntington's disease.

Brain and behavior - 1 Sept 2014

Skillings Elizabeth A, Wood Nigel I, Morton A Jennifer

Abstract excerpt

BACKGROUND: In addition to their cognitive and motor deficits, R6/2 mice show a progressive disintegration in circadian rhythms that mirrors the problems associated with sleep-wake disturbances experienced by patients with Huntington's disease (HD). It has been shown previously that motor and cognitive performance, as well as survival, can be improved in transgenic mouse models of HD through the provision of...

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Identifiers

PMID: 25328844
DOI: 10.1002/brb3.235
PMCID: PMC4107380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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