Article
Beneficial effects of environmental enrichment and food entrainment in the R6/2 mouse model of Huntington's disease.
Brain and behavior - 1 Sept 2014
Skillings Elizabeth A, Wood Nigel I, Morton A Jennifer
Abstract excerpt
BACKGROUND: In addition to their cognitive and motor deficits, R6/2 mice show a progressive disintegration in circadian rhythms that mirrors the problems associated with sleep-wake disturbances experienced by patients with Huntington's disease (HD). It has been shown previously that motor and cog...
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