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Article

Environmental stimulation increases survival in mice transgenic for exon 1 of the Huntington's disease gene.

Movement disorders : official journal of the Movement Disorder Society - 1 Sept 2000

Carter R J, Hunt M J, Morton A J

Abstract excerpt

Mice transgenic for the first exon of the human Huntington's disease (HD) gene carrying an expanded CAG repeat expansion (R6/2 line) develop a progressive neurologic phenotype with symptoms resembling those seen in HD. The overt symptoms of R6/2 mice worsen with age, resulting in a rapid decline in health and premature death between 13 and 18 weeks of age. In this study, we characterized the onset and progression...

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Identifiers

PMID: 11009201
DOI: 10.1002/1531-8257(200009)15:5<925::aid-mds1025>3.0.co;2-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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