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Lead Structures for New Antibacterials: Stereocontrolled Synthesis of a Bioactive Muraymycin Analogue

15 Oct 2014

Abstract excerpt

Naturally occurring muraymycin nucleoside antibiotics represent a promising class of novel antibacterial agents. The structural complexity suggests the investigation of simplified analogues as potential lead structures, which can then be further optimized towards highly potent antimicrobials. Herein we report studies on muraymycin-derived potential lead structures lacking an aminoribose motif found in most...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25318977
DOI: 10.1002/chem.201404775

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