Article
Atopic dermatitis: epidemiology and pathogenesis update.
Seminars in cutaneous medicine and surgery - 1 Sept 2012
Eichenfield Lawrence F, Ellis Charles N, Mancini Anthony J, Paller Amy S, Simpson Eric L
Abstract excerpt
The prevalence of atopic dermatitis (AD) has increased markedly in the United States over the past 5 decades, with current reports varying from 10% to 20% prevalence in US children, and new diagnoses are estimated at almost 11% per year. Recent research in AD pathophysiology and pathogenesis has demonstrated that AD is associated with epidermal barrier dysfunction and that mutations in the filaggrin gene are...
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