Article
Transmission of the human mitochondrial genome.
Human reproduction (Oxford, England) - 1 Jul 2000
Howell N, Chinnery P F, Ghosh S S, Fahy E, Turnbull D M
Abstract excerpt
The segregation and transmission of mitochondrial genomes in humans are complicated processes, but are particularly important for understanding the inheritance and clinical abnormalities of mitochondrial disorders. This review describes three aspects of mitochondrial genetics. First, that the segregation and transmission of mitochondrial (mt)DNA molecules are likely to be determined by their physical association...
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