Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Genetic determinants of response to vitamin K antagonists].

Giornale italiano di cardiologia (2006) - 1 Sept 2014

Mundi Santa, Distante Alessandro, De Caterina Raffaele

Abstract excerpt

The narrow therapeutic index, the large interindividual variability, and the severity of adverse drug reactions connected with vitamin K antagonists, together with their ample use in medical therapy, have prompted the search for strategies to better assist doctors in the choice of the safest and most effective dose of these drugs. The molecular mechanism by which oral anticoagulants exert their effect is an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticoagulants
Share to Biotransformation
Share to Cytochrome P-450 CYP2C9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Vitamin K

Share to Vitamin K Epoxide Reductases

Source

Identifiers

PMID: 25298357
DOI: 10.1714/1640.17974

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Genetic determinants of response to vitamin K antagonists].PMID 25298357Read ↗

[Pharmacogenetic algorithms for predicting the appropriate dose of vitamin K antagonists: are they still useful?].Semantic proximity Read ↗

[Pharmacogenomics of vitamin K antagonists].Semantic proximity Read ↗

[The pharmacogenetics of vitamin K antagonists: still a matter for discussion].Semantic proximity Read ↗

[Impact of pharmacogenetics on interindividual variability in the response to vitamin K antagonist therapy].Semantic proximity Read ↗

[Oral anticoagulation and pharmacogenetics: importance in the clinical setting].Semantic proximity Read ↗

Oral anticoagulants: Pharmacogenetics Relationship between genetic and non-genetic factors.Semantic proximity Read ↗

Pharmacogenetics aspects of oral anticoagulants therapy.Semantic proximity Read ↗

Pharmacogenetics of warfarin: current status and future challenges.Semantic proximity Read ↗

[Genetic predisposition to bleeding during oral anticoagulants treatment].Semantic proximity Read ↗

Investigating warfarin variability : the contribution of clinical, genetic, and environmental factorsSemantic proximity Read ↗

Warfarin therapy: influence of pharmacogenetic and environmental factors on the anticoagulant response to warfarin.Semantic proximity Read ↗

Use of Pharmacogenetic Information in the Treatment of Cardiovascular Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.