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Article

[Pharmacogenomics of vitamin K antagonists].

Revista medica de Chile - 1 Sept 2020

Guzmán Neftalí, Vega Mario, Reyes Franco, Guzmán-Oyarzo Dina, Andaur Marcela, Boguen Rodrigo, Letelier Pablo

Abstract excerpt

There is an important interindividual variability in dose requirement for coumarinic anticoagulants, which could be explained by genetic and non-genetic factors. Among hereditary factors, there are gene polymorphisms that code the therapeutic target and the main enzyme responsible for their metabolism. However, there are other candidate genes that could modulate dose requirements. The is a paucity of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33399707
DOI: 10.4067/S0034-98872020000901307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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