Article
Association of NLRP3 single nucleotide polymorphisms with ulcerative colitis: A case-control study.
Clinics and research in hepatology and gastroenterology - 1 Jun 2018
Hanaei S, Sadr M, Rezaei A, Shahkarami S, Ebrahimi Daryani N, Bidoki A Z, Rezaei N
Abstract excerpt
BACKGROUND: Ulcerative colitis (UC) is inflammatory bowel disease (IBD), characterized by chronic inflammation episodes within mucosal layer of the intestine mostly affecting colon and rectum. As the role of innate immunity in pathogenesis of disease and important role of NLRP3, the aim of this study is to investigate the association of NLRP3 SNPs with UC in Iranian patients. METHODS: Blood samples from 45 UC...
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