Article
An association study on the CHRNA5/A3/B4 gene cluster, smoking and psoriasis vulgaris.
Archives of dermatological research - 1 Dec 2014
Zhu Kun-Ju, Liu Zhong, Liu Huan, Li Shi-Jie, Zhu Cheng-Yao, Li Ke-Shen, Fan Yi-Ming
Abstract excerpt
Genome-wide association and large cohort studies have consistently linked several single nucleotide polymorphisms (SNPs) located in the CHRNA5/A3/B4 gene cluster to smoking behaviors and nicotine dependence. Smoking is one of the well-established environmental risk factors for psoriasis and also associated with severity of the disease. Then we conduct the study to examine whether the genetic variations related to...
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