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Dietary supplementation with polyunsaturated fatty acid during pregnancy modulates DNA methylation at <i>IGF2/H19</i> imprinted genes and growth of infants

8 Oct 2014

Abstract excerpt

Epigenetic regulation of imprinted genes is regarded as a highly plausible explanation for linking dietary exposures in early life with the onset of diseases during childhood and adulthood. We sought to test whether prenatal dietary supplementation with docosahexaenoic acid (DHA) during pregnancy may modulate epigenetic states at birth. This study was based on a randomized intervention trial conducted in Mexican...

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PMID: 25293351
DOI: 10.1152/physiolgenomics.00061.2014

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