Article
Metabolic Programming of <i>MEST</i> DNA Methylation by Intrauterine Exposure to Gestational Diabetes Mellitus
4 Dec 2012
Abstract excerpt
Epigenetic processes are primary candidates when searching for mechanisms that can stably modulate gene expression and metabolic pathways according to early life conditions. To test the effects of gestational diabetes mellitus (GDM) on the epigenome of the next generation, cord blood and placenta tissue were obtained from 88 newborns of mothers with dietetically treated GDM, 98 with insulin-dependent GDM, and 65...
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