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Article

Mapping the accumulation of co-infiltrating CNS dendritic cells and encephalitogenic T cells during EAE.

Journal of neuroimmunology - 15 Dec 2014

Clarkson Benjamin D, Walker Alec, Harris Melissa, Rayasam Aditya, Sandor Matyas, Fabry Zsuzsanna

Abstract excerpt

Evidence from experimental autoimmune encephalomyelitis (EAE) suggests that CNS-infiltrating dendritic cells (DCs) are crucial for restimulation of coinfiltrating T cells. Here we systematically quantified and visualized the distribution and interaction of CNS DCs and T cells during EAE. We report marked periventricular accumulation of DCs and myelin-specific T cells during EAE disease onset prior to accumulation...

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Source

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Identifiers

PMID: 25288303
DOI: 10.1016/j.jneuroim.2014.09.016
PMCID: PMC4250311

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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