Article
Vitamin D receptor haplotypes affect lead levels during pregnancy.
The Science of the total environment - 1 Oct 2010
Rezende Vania B, Amaral Jefferson H, Quintana Silvana M, Gerlach Raquel F, Barbosa Fernando, Tanus-Santos Jose E
Abstract excerpt
Pregnant women are particularly susceptible to toxic effects associated with lead (Pb) exposure. Pb accumulates in bone tissue and is rapidly mobilized from bones during pregnancy, thus resulting in fetal contamination. While vitamin D receptor (VDR) polymorphisms modify bone mineralization and affect Pb biomarkers including blood (Pb-B) and serum (Pb-S) Pb concentrations, and %Pb-S/Pb-B ratio, the effects of...
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