Article
Global fibrinolytic activity, PAI-1 level, and 4G/5G polymorphism in Thai children with arterial ischemic stroke.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Jan 2000
Natesirinilkul Rungrote, Sasanakul Werasak, Chuansumrit Ampaiwan, Kadegasem Praguywan, Visudtibhan Anannit, Wongwerawattanakoon Pakawan, Sirachainan Nongnuch
Abstract excerpt
BACKGROUND: Prolonged euglobulin clot lysis time (ECLT) and increased level of plasminogen activator inhibitor-1 (PAI-1) were reported to be risk factors of arterial ischemic stroke (AIS) by some studies; however, these findings were not supported by other studies. The objective of this study was to determine the association of ECLT, PAI-1 level, and polymorphisms of 4G and 5G of PAI-1 gene to the development of...
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