Article
Investigation of Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G promoter polymorphism in Indian venous thrombosis patients: A case-control study.
European journal of haematology - 1 Sept 2017
Prabhudesai Aniket, Shetty Shrimati, Ghosh Kanjaksha, Kulkarni Bipin
Abstract excerpt
BACKGROUND: The role of PAI-1 4G/5G polymorphism in venous thrombosis has been contradictory. PAI-1 4G/4G genotype is associated with elevated levels of PAI-1 resulting in a hypofibrinolytic state and a higher thrombotic risk. OBJECTIVE: In this study, the distribution of genotypes and frequency of alleles of the 4G/5G polymorphism of PAI-1 gene in Indian patients with different types of venous thrombosis was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
