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Article

Plasminogen activator inhibitor-1 (PAI-1) 4G/5G promoter polymorphisms and risk of venous thromboembolism - a meta-analysis and systematic review.

VASA. Zeitschrift fur Gefasskrankheiten - 1 Mar 2020

Zhang Qiang, Jin YunRui, Li XueMei, Peng XingQiao, Peng Na, Song JiFang, Xu Mingfang

Abstract excerpt

Background: A 4G/5G polymorphism in the promoter region of the plasminogen activator inhibitor type 1 (PAI-1) gene has been reported to enhance the plasma levels of PAI-1, which plays an important role in fibrinolysis disorders and venous thromboembolism, but a large number of studies have reported inconclusive results. Therefore, we performed a meta-analysis to analysis these associations. Materials and methods:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31920171
DOI: 10.1024/0301-1526/a000839

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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