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Article

CYCLIN-DEPENDENT KINASE8 differentially regulates plant immunity to fungal pathogens through kinase-dependent and -independent functions in Arabidopsis.

The Plant cell - 1 Oct 2014

Zhu Yingfang, Schluttenhoffer Craig M, Wang Pengcheng, Fu Fuyou, Thimmapuram Jyothi, Zhu Jian-Kang, Lee Sang Yeol, Yun Dae-Jin, Mengiste Tesfaye

Abstract excerpt

CYCLIN-DEPENDENT KINASE8 (CDK8) is a widely studied component of eukaryotic Mediator complexes. However, the biological and molecular functions of plant CDK8 are not well understood. Here, we provide evidence for regulatory functions of Arabidopsis thaliana CDK8 in defense and demonstrate its functional and molecular interactions with other Mediator and non-Mediator subunits. The cdk8 mutant exhibits enhanced...

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Source

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Identifiers

PMID: 25281690
DOI: 10.1105/tpc.114.128611
PMCID: PMC4247566

Genes

CDK8
MED12
MED13
MED25

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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