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Article

Differential efficacy of human mesenchymal stem cells based on source of origin.

Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 2014

Collins Erin, Gu Fei, Qi Maosong, Molano Ivan, Ruiz Phillip, Sun Lingyun, Gilkeson Gary S

Abstract excerpt

Mesenchymal stem cells (MSCs) are useful in tissue repair but also possess immunomodulatory properties. Murine and uncontrolled human trials suggest efficacy of MSCs in treating lupus. Autologous cells are preferable; however, recent studies suggest that lupus-derived MSCs lack efficacy in treating disease. Thus, the optimum derivation of MSCs for use in lupus is unknown. It is also unknown which in vitro assays...

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Identifiers

PMID: 25274529
DOI: 10.4049/jimmunol.1401636
PMCID: PMC4201962

Genes

MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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