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Universal or Personalized Mesenchymal Stem Cell Therapies: Impact of Age, Sex, and Biological Source

30 Jun 2022

Abstract excerpt

Mesenchymal stem/stromal cells (MSCs) hold great promise for the treatment of autoimmune conditions given their immunomodulatory properties. Based on the low immunogenicity of MSCs, it is tempting to consider the expansion of MSCs from a "universal donor" in culture prior to their allogeneic applications for immediate care. This raises the critical question of the criteria we should use to select the best...

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PMID: 35805161
DOI: 10.3390/cells11132077

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