Article
LC-MS-based urinary metabolite signatures in idiopathic Parkinson's disease.
Journal of proteome research - 2 Jan 2015
Luan Hemi, Liu Liang-Feng, Meng Nan, Tang Zhi, Chua Ka-Kit, Chen Lei-Lei, Song Ju-Xian, Mok Vincent C T, Xie Li-Xia, Li Min, Cai Zongwei
Abstract excerpt
Increasing evidence has shown that abnormal metabolic phenotypes in body fluids reflect the pathogenesis and pathophysiology of Parkinson's disease (PD). These body fluids include urine; however, the relationship between, specifically, urinary metabolic phenotypes and PD is not fully understood. In this study, urinary metabolites from a total of 401 clinical urine samples collected from 106 idiopathic PD patients...
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