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Article

Metabolomic profiling in LRRK2-related Parkinson's disease.

PloS one - 22 Oct 2009

Johansen Krisztina K, Wang Lei, Aasly Jan O, White Linda R, Matson Wayne R, Henchcliffe Claire, Beal M Flint, Bogdanov Mikhail

Abstract excerpt

BACKGROUND: Mutations in LRRK2 gene represent the most common known genetic cause of Parkinson's disease (PD). METHODOLOGY/PRINCIPAL FINDINGS: We used metabolomic profiling to identify biomarkers that are associated with idiopathic and LRRK2 PD. We compared plasma metabolomic profiles of patients with PD due to the G2019S LRRK2 mutation, to asymptomatic family members of these patients either with or without...

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Identifiers

PMID: 19847307
DOI: 10.1371/journal.pone.0007551
PMCID: PMC2761616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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