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Article

MicroRNA-193a Regulates the Transdifferentiation of Human Parietal Epithelial Cells toward a Podocyte Phenotype.

Journal of the American Society of Nephrology : JASN - 1 Jun 2015

Kietzmann Leonie, Guhr Sebastian S O, Meyer Tobias N, Ni Lan, Sachs Marlies, Panzer Ulf, Stahl Rolf A K, Saleem Moin A, Kerjaschki Dontscho, Gebeshuber Christoph A, Meyer-Schwesinger Catherine

Abstract excerpt

Parietal epithelial cells have been identified as potential progenitor cells in glomerular regeneration, but the molecular mechanisms underlying this process are not fully defined. Here, we established an immortalized polyclonal human parietal epithelial cell (hPEC) line from naive human Bowman's capsule cells isolated by mechanical microdissection. These hPECs expressed high levels of PEC-specific proteins and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fluorescent Antibody Technique

Share to Glomerulosclerosis, Focal Segmental

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Source

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Identifiers

PMID: 25270065
DOI: 10.1681/ASN.2014020190
PMCID: PMC4446868

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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