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Article

RAD51B plays an essential role during somatic and meiotic recombination in Physcomitrella.

Nucleic acids research - 29 Oct 2014

Charlot Florence, Chelysheva Liudmila, Kamisugi Yasuko, Vrielynck Nathalie, Guyon Anouchka, Epert Aline, Le Guin Sylvia, Schaefer Didier G, Cuming Andrew C, Grelon Mathilde, Nogué Fabien

Abstract excerpt

The eukaryotic RecA homologue Rad51 is a key factor in homologous recombination and recombinational repair. Rad51-like proteins have been identified in yeast (Rad55, Rad57 and Dmc1), plants and vertebrates (RAD51B, RAD51C, RAD51D, XRCC2, XRCC3 and DMC1). RAD51 and DMC1 are the strand-exchange proteins forming a nucleofilament for strand invasion, however, the function of the paralogues in the process of...

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Source

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Identifiers

PMID: 25260587
DOI: 10.1093/nar/gku890
PMCID: PMC4231755

Genes

DMC1
RAD51
XRCC2
XRCC3

Provenance

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