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Article

Managing common symptoms of cerebral palsy in children

25 Sept 2014

Abstract excerpt

<h3>Abstract</h3> Type 1 diabetes (T1D) is an autoimmune disease that results in the destruction of insulin producing pancreatic β-cells. One of the genes associated with T1D is <i>TYK2,</i> which encodes a Janus kinase with critical roles in type-Ι interferon (IFN) mediated intracellular signaling. To study the role of TYK2 in human pancreatic β-cell development and response to IFNα, we generated <i>TYK2</i>...

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PMID: 25255910
DOI: 10.1136/bmj.g5474

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