Article
Role of transforming growth factor-β1 -509 C/T promoter polymorphism in gastric cancer in south Indian population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2011
Bhayal Amar Chand, Prabhakar B, Rao K Pandu Ranga, Penchikala Anitha, Ayesha Qamar, Jyothy A, Nallari Pratibha, Venkateshwari A
Abstract excerpt
Gastric cancer is a multifactorial disease with the involvement of both genetic and environmental risk factors. Genetic variation in genes encoding cytokines and their receptors determine the intensity of the inflammatory response, which may contribute to individual differences in the outcome and severity of the disease. Transforming growth factor (TGF-β) signaling pathway plays an important role in the genesis...
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