Article
Stabilization of disease after targeted therapy in a thymic carcinoma with KIT mutation detected by clinical next-generation sequencing.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Feb 2014
Hagemann Ian S, Govindan Ramaswamy, Javidan-Nejad Cylen, Pfeifer John D, Cottrell Catherine E
Abstract excerpt
Precision medicine uses individually determined genomic information to guide treatment in cancer and other diseases. We have implemented a clinical genomics assay that uses targeted next-generation sequencing of 25 cancer-related genes to guide the use of targeted therapies in diverse malignancies. We report the case of a 55-year-old woman with a poorly differentiated squamous cell carcinoma of thymic origin,...
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