Article
Identification of the regulatory logic controlling Salmonella pathoadaptation by the SsrA-SsrB two-component system.
PLoS genetics - 12 Mar 2010
Tomljenovic-Berube Ana M, Mulder David T, Whiteside Matthew D, Brinkman Fiona S L, Coombes Brian K
Abstract excerpt
Sequence data from the past decade has laid bare the significance of horizontal gene transfer in creating genetic diversity in the bacterial world. Regulatory evolution, in which non-coding DNA is mutated to create new regulatory nodes, also contributes to this diversity to allow niche adaptation and the evolution of pathogenesis. To survive in the host environment, Salmonella enterica uses a type III secretion...
Topics
- Adaptation, Physiological
- Bacterial Proteins
- Base Sequence
- Chromatin Immunoprecipitation
- Conserved Sequence
- DNA, Bacterial
- Evolution, Molecular
- Gene Expression Profiling
- Gene Expression Regulation, Bacterial
- Genetic Loci
- Genome, Bacterial
- Genomic Islands