Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of copper supplementation on the structure and content of elements in kidneys of mosaic mutant mice.

Biological trace element research - 1 Aug 2010

Lenartowicz Małgorzata, Windak Renata, Tylko Grzegorz, Kowal Małgorzata, Styrna Józefa

Abstract excerpt

Menkes disease is an effect of ATP7A gene mutation in humans, coding the Cu-ATP-ase which is essential in intestinal copper absorption and its subsequent transfer to circulation. This mutation results in a deficiency of copper in all tissues except the epithelia of intestine and kidney tubules. Subcutaneous injection of copper ions is the main therapy for Menkes patients. Mosaic (Atp7a(mo-ms)) mice closely...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to Cation Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Copper

Share to Copper-Transporting ATPases

Share to Dietary Supplements

Share to Longevity

Share to Menkes Kinky Hair Syndrome

Share to Trace Elements

Source

Identifiers

PMID: 19830392
DOI: 10.1007/s12011-009-8533-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of copper supplementation on the structure and content of elements in kidneys of mosaic mutant mice.PMID 19830392Read ↗

Alterations in the expression of the Atp7a gene in the early postnatal development of the mosaic mutant mice (Atp7a mo-ms) - An animal model for Menkes disease.Semantic proximity Read ↗

Alterations in kidney morphology in mice with mosaic mutation.Semantic proximity Read ↗

Prenatal treatment of mosaic mice (Atp7a mo-ms) mouse model for Menkes disease, with copper combined by dimethyldithiocarbamate (DMDTC).Semantic proximity Read ↗

Mutation in the CPC motif-containing 6th transmembrane domain affects intracellular localization, trafficking and copper transport efficiency of ATP7A protein in mosaic mutant mice--an animal model of Menkes disease.Semantic proximity Read ↗

Phenotypic and genetic characterization of the Atp7a(Mo-Tohm) mottled mouse: a new murine model of Menkes disease.Semantic proximity Read ↗

Copper deficiencySemantic proximity Read ↗

Copper storage diseases: Menkes, Wilsons, and cancer.Semantic proximity Read ↗

Menkes disease: Oral administration of glyoxal-bis(N(4)-methylthiosemicarbazonato)-copper(II) rescues the macular mouse.Semantic proximity Read ↗

Menkes disease.Semantic proximity Read ↗

Copper transport and its alterations in Menkes and Wilson diseases.Semantic proximity Read ↗

[Copper metabolism and genetic disorders].Semantic proximity Read ↗

Menkes disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.