Article
Basis for substrate recognition and distinction by matrix metalloproteinases.
Proceedings of the National Academy of Sciences of the United States of America - 7 Oct 2014
Ratnikov Boris I, Cieplak Piotr, Gramatikoff Kosi, Pierce James, Eroshkin Alexey, Igarashi Yoshinobu, Kazanov Marat, Sun Qing, Godzik Adam, Osterman Andrei, Stec Boguslaw, Strongin Alex, Smith Jeffrey W
Abstract excerpt
Genomic sequencing and structural genomics produced a vast amount of sequence and structural data, creating an opportunity for structure-function analysis in silico [Radivojac P, et al. (2013) Nat Methods 10(3):221-227]. Unfortunately, only a few large experimental datasets exist to serve as benchmarks for function-related predictions. Furthermore, currently there are no reliable means to predict the extent of...
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