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Article

A coding variant in SR-BI (I179N) significantly increases atherosclerosis in mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2013

Picataggi Antonino, Lim Geoffrey F, Kent Anthony P, Millar John S, Rader Daniel J, Stylianou Ioannis M

Abstract excerpt

Human coding variants in scavenger receptor class B member 1 (SR-BI; gene name SCARB1) have recently been identified as being associated with plasma levels of HDL cholesterol. However, a link between coding variants and atherosclerosis has not yet been established. In this study we set out to exa...

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Share to Atherosclerosis
Share to Cholesterol, HDL
Share to Cholesterol, LDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Receptors, LDL

Share to Scavenger Receptors, Class B

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Source

Identifiers

PMID: 23722970
DOI: 10.1007/s00335-013-9459-x

Genes

SCARB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23722970-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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