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Article

Association between leukocyte mitochondrial DNA content and risk of coronary heart disease: a case-control study.

Atherosclerosis - 1 Nov 2014

Chen Shuying, Xie Xuejian, Wang Yujing, Gao Yan, Xie Xiaoli, Yang Jing, Ye Jixian

Abstract excerpt

OBJECTIVE: Compelling epidemiological evidence indicates that alterations of mitochondrial DNA (mtDNA), including mutations and abnormal content of mtDNA, are associated with the initiation and development of cardiovascular disease. This study was undertaken to investigate whether mtDNA content in peripheral blood leukocytes (PBLs) could be used as a risk predictor for coronary heart disease (CHD). METHODS: The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25244506
DOI: 10.1016/j.atherosclerosis.2014.08.051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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